ARAP2

Across TCGA cell cohorts, ARAP2 mutation is significantly associated with the RNA expression of many other genes, with 1,302 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARAP2-associated genes across cancer lineages are PSKH2, PRKAG3, and TAAR6. Each is linked with ARAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARAP2-to-partner and partner-to-ARAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSKH2 grouped by ARAP2-low versus ARAP2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARAP2→partner) and Y-score (partner→ARAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PSKH2 →	+0.010	+2.302	<.001	.005	3	2
BLOOD_Leukemia	PRKAG3 →	+0.023	+3.288	<.001	<.001	3	2
BLOOD_Leukemia	TAAR6 →	+0.009	+2.922	<.001	.009	3	2
LARGE_INTESTINE	PPP3CB →	+0.498	+3.169	<.001	.006	3	2
LARGE_INTESTINE	BAG2 →	+1.131	+3.584	<.001	<.001	3	2
LARGE_INTESTINE	RNF19B →	+0.616	+3.234	.009	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,302 associations by consensus.

PSKH2 by ARAP2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →