ARAP1-AS2

Across TCGA pan-cancer cohorts, ARAP1-AS2 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ARAP1-AS2 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ARAP1-AS2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ARAP1-AS2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

HNSC, KIRP, and UVM are the cancer types where ARAP1-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Quartile	IV	0.449	0.208	.001	83	view →
KIRP	DFS	Median	All	0.571	0.672	.007	47	view →
UVM	DFS	Quartile	III,IV	0.129	0.908	<.001	42	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
THCA	OS	Median	II,III,IV	0.896	0.984	<.001	23	view →
LGG	DFS	Quartile	All	0.315	0.469	.001	22	view →
KIRC	DFS	Median	All	0.560	0.677	.005	20	view →
MESO	DFS	Median	II,III,IV	0.292	0.608	.009	18	view →
SKCM	OS	Quartile	III,IV	0.618	0.282	.003	15	view →
ACC	OS	Median	II,III,IV	0.862	0.407	.010	15	view →
BRCA	OS	Tertile	III,IV	0.750	0.382	.001	13	view →
LIHC	DFS	Quartile	All	0.411	0.586	.002	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ARAP1-AS2–HNSC (DFS)

Open the HNSC breakdown →