ARAP1-AS1

Across TCGA pan-cancer cohorts, ARAP1-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated ARAP1-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ARAP1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ARAP1-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and READ show a favorable association.

UVM, SKCM, and CHOL are the cancer types where ARAP1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.580	0.884	.001	99	view →
SKCM	OS	Tertile	IV	0.479	0.832	.001	38	view →
CHOL	OS	Quartile	II,III,IV	0.144	0.788	<.001	37	view →
COAD	DFS	Tertile	II,III,IV	0.287	0.605	.005	36	view →
KIRC	DFS	Quartile	All	0.541	0.687	.007	31	view →
MESO	OS	Tertile	IV	0.257	0.693	.003	27	view →
BLCA	DFS	Median	IV	0.340	0.151	.010	19	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
BRCA	DFS	Tertile	IV	0.299	0.621	.021	18	view →
READ	DFS	Median	All	0.933	0.696	.015	13	view →
ESCA	OS	Quartile	IV	0.135	0.674	.038	12	view →
KIRP	DFS	Quartile	II,III,IV	0.209	0.757	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

ARAP1-AS1–UVM (OS)

Open the UVM breakdown →