AR

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, AR mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated AR data layer compared with 29 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher AR mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated AR expression acts as an unfavorable survival marker.

UCEC, CCRCC, and LSCC are the cancer types where AR mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianIII,IV0.3121.000.00324view →
CCRCCDFSTertileII,III,IV0.7531.000.0192view →
LSCCDFSTertileAll0.4301.000.0182view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

AR–UCEC (OS)

Kaplan–Meier survival curve for AR mass-spec protein-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration