AQR

Across TCGA patient cohorts, AQR RNA expression is significantly associated with the protein abundance of many other proteins, with 15,214 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AQR-associated proteins across cancer lineages are RTF1, SRP14, and SDF2L1. Each is linked with AQR in more than 6 cancer types. Because this analysis shows association rather than direction, both AQR-to-partner and partner-to-AQR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AQR versus RTF1 in LSCC, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AQR→partner) and Y-score (partner→AQR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RTF1 →	+0.286	+0.437	<.001	<.001	3	7
GBM	SRP14 →	+0.270	+0.264	<.001	<.001	3	6
CCRCC	SDF2L1 →	-0.481	-0.315	<.001	<.001	3	6
GBM	CALR →	-0.309	-0.273	<.001	<.001	3	6
LSCC	DNAJC17 →	+0.338	+0.523	<.001	<.001	3	6
BRCA	UBE3A →	+0.266	+0.428	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,214 associations by consensus.

AQR vs RTF1 — LSCC

Explore this scatter interactively →