AQP9

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AQP9 RNA expression is significantly associated with the protein abundance of many other proteins, with 25,536 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AQP9-associated proteins across cancer lineages are PRAM1_S484, PRTN3, and PADI4. Each is linked with AQP9 in more than 8 cancer types. Because this analysis shows association rather than direction, both AQP9-to-partner and partner-to-AQP9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AQP9 versus PRAM1_S484 in UCEC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP9→partner) and Y-score (partner→AQP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPRAM1_S484 →+0.911+1.038<.001<.00139
BRCAPRTN3 →+1.754+1.659<.001<.00139
GBMPADI4 →+1.329+1.440<.001<.00139
PDACPGLYRP1 →+1.239+1.093<.001<.00139
GBMS100A12 →+1.574+1.444<.001<.00139
PDACITGAM →+0.874+1.448<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 25,536 associations by consensus.

AQP9 vs PRAM1_S484 — UCEC

Per-sample scatter of AQP9 vs PRAM1_S484 in UCEC (Pearson r = 0.57).

Explore this scatter interactively →

Exploration