AQP9

Across TCGA patient cohorts, AQP9 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,944 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AQP9-associated proteins across cancer lineages are AKAP13_S650, APAF1, and APOBR_S175. Each is linked with AQP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both AQP9-to-partner and partner-to-AQP9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AQP9 versus AKAP13_S650 in LSCC, with a Pearson correlation of 0.69.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP9→partner) and Y-score (partner→AQP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKAP13_S650 →	+0.567	+1.118	<.001	<.001	3	1
LSCC	APAF1 →	+0.459	+1.173	<.001	<.001	3	1
LSCC	APOBR_S175 →	+1.257	+1.194	<.001	<.001	3	1
LSCC	APTX_S118 →	+0.741	+0.979	.001	<.001	3	1
LSCC	RETN →	+1.618	+1.390	<.001	<.001	3	1
LSCC	RFLNB →	+0.512	+1.071	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,944 associations by consensus.

AQP9 vs AKAP13_S650 — LSCC

Explore this scatter interactively →