AQP7P2

Across TCGA pan-cancer cohorts, AQP7P2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated AQP7P2 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher AQP7P2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated AQP7P2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and KIRP show a favorable association.

THCA, UVM, and LUSC are the cancer types where AQP7P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.814	0.952	<.001	96	view →
UVM	OS	Tertile	All	0.275	0.940	<.001	90	view →
LUSC	OS	Tertile	All	0.190	0.428	<.001	84	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	48	view →
ACC	OS	Quartile	All	0.389	0.715	.002	48	view →
LUAD	OS	Tertile	II,III,IV	0.349	0.695	.005	42	view →
KICH	OS	Tertile	II,III,IV	0.155	0.880	<.001	18	view →
SKCM	OS	Quartile	III,IV	0.580	0.313	.009	9	view →
LIHC	DFS	Quartile	III,IV	0.196	0.468	.027	6	view →
DLBC	DFS	Tertile	All	0.297	0.657	.020	6	view →
STAD	DFS	Median	All	0.464	0.585	.038	5	view →
KIRC	OS	Quartile	II,III,IV	0.403	0.583	.023	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

AQP7P2–THCA (OS)

Open the THCA breakdown →