AQP7

Across TCGA patient cohorts, AQP7 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,996 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AQP7-associated proteins across cancer lineages are CRYL1, DNMT1_S714, and SH3BGRL2. Each is linked with AQP7 in more than 5 cancer types. Because this analysis shows association rather than direction, both AQP7-to-partner and partner-to-AQP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AQP7 versus CRYL1 in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP7→partner) and Y-score (partner→AQP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CRYL1 →	+0.510	+0.711	<.001	<.001	3	6
CCRCC	DNMT1_S714 →	-0.581	-1.179	.001	<.001	3	6
BRCA	SH3BGRL2 →	+0.621	+1.216	<.001	<.001	3	6
PDAC	ABLIM1 →	+0.449	+0.529	<.001	<.001	3	6
COAD	NAXD →	+0.337	+0.889	<.001	<.001	3	5
OV	TNS2_S120 →	+0.496	+0.712	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,996 associations by consensus.

AQP7 vs CRYL1 — UCEC

Explore this scatter interactively →