AQP7

Across TCGA cell cohorts, AQP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,482 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AQP7-associated GO terms across cancer lineages are Cellular response to ketone, Leukotriene B4 catabolic process, and Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Each is linked with AQP7 in more than 8 cancer types. Because this analysis shows association rather than direction, both AQP7-to-partner and partner-to-AQP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to ketone grouped by AQP7-low versus AQP7-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP7→partner) and Y-score (partner→AQP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Cellular response to ketone →	+0.092	+1.260	<.001	<.001	3	9
LARGE_INTESTINE	Leukotriene B4 catabolic process →	+1.253	+1.301	<.001	<.001	3	8
STOMACH	Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.146	+0.890	<.001	.009	2	8
LIVER	Dopamine metabolic process →	+0.219	+1.849	.009	.003	2	8
LIVER	Cholesterol homeostasis →	+0.121	+1.361	<.001	<.001	3	7
LARGE_INTESTINE	Pressure natriuresis →	+1.125	+1.048	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,482 associations by consensus.

Cellular response to ketone by AQP7 expression — LARGE_INTESTINE

Explore this box plot interactively →