AQP6

Across TCGA patient cohorts, AQP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,136 significant associations in total. THCA shows the largest number of these associations.

The most reproducible AQP6-associated GO terms across cancer lineages are Renal water transport, Regulation of DNA recombination, and Somite development. Each is linked with AQP6 in more than 14 cancer types. Because this analysis shows association rather than direction, both AQP6-to-partner and partner-to-AQP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal water transport grouped by AQP6-low versus AQP6-high in PAAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP6→partner) and Y-score (partner→AQP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	Renal water transport →	-0.069	-0.594	<.001	<.001	3	15
STAD	Regulation of DNA recombination →	+0.052	+0.208	<.001	<.001	3	14
STAD	Somite development →	+0.039	+0.156	<.001	.001	3	14
ESCA	Glycerolipid biosynthetic process →	+0.052	+0.510	<.001	<.001	3	14
STAD	Positive regulation of DNA repair →	+0.059	+0.229	<.001	<.001	3	14
STAD	Cytokinesis →	+0.060	+0.243	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,136 associations by consensus.

Renal water transport by AQP6 expression — PAAD

Explore this box plot interactively →