AQP6

Across TCGA patient cohorts, AQP6 protein abundance is significantly associated with the RNA expression of many other genes, with 207 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible AQP6-associated genes across cancer lineages are SRRD, KCTD17, and SYTL4. Each is linked with AQP6 in more than 1 cancer types. Because this analysis shows association rather than direction, both AQP6-to-partner and partner-to-AQP6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AQP6 versus SRRD in HNSC, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP6→partner) and Y-score (partner→AQP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SRRD →	-1.061	-1.556	.003	<.001	3	1
HNSC	KCTD17 →	-1.191	-1.228	.004	.007	3	1
HNSC	SYTL4 →	-0.669	-0.935	.008	.003	3	1
HNSC	USB1 →	-0.671	-1.186	<.001	.007	3	1
HNSC	VAC14 →	-0.968	-1.299	.002	.006	3	1
HNSC	TTC23 →	-0.605	-1.055	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 207 associations by consensus.

AQP6 vs SRRD — HNSC

Explore this scatter interactively →