AQP6

Across TCGA cell cohorts, AQP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,855 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible AQP6-associated GO terms across cancer lineages are Nitrate transmembrane transport, Nitrate import, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with AQP6 in more than 11 cancer types. Because this analysis shows association rather than direction, both AQP6-to-partner and partner-to-AQP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nitrate transmembrane transport grouped by AQP6-low versus AQP6-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP6→partner) and Y-score (partner→AQP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Nitrate transmembrane transport →	+0.191	+0.637	<.001	<.001	3	12
STOMACH	Nitrate import →	+0.191	+0.637	<.001	<.001	3	12
SKIN	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.131	+0.405	<.001	<.001	3	7
SKIN	ATP metabolic process →	+0.065	+0.245	<.001	.004	3	6
SKIN	Purine ribonucleoside triphosphate metabolic process →	+0.079	+0.347	<.001	<.001	3	6
BONE	Cilium movement →	-0.091	-0.107	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,855 associations by consensus.

Nitrate transmembrane transport by AQP6 expression — STOMACH

Explore this box plot interactively →