AQP3

Across TCGA cell cohorts, AQP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,248 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AQP3-associated GO terms across cancer lineages are Urea transmembrane transport, Urea transport, and Glycerol transmembrane transport. Each is linked with AQP3 in more than 18 cancer types. Because this analysis shows association rather than direction, both AQP3-to-partner and partner-to-AQP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Urea transmembrane transport grouped by AQP3-low versus AQP3-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP3→partner) and Y-score (partner→AQP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Urea transmembrane transport →	+2.334	+4.286	<.001	<.001	3	19
LUNG_NSCLC_LUAD	Urea transport →	+2.357	+4.286	<.001	<.001	3	19
URINARY_TRACT	Glycerol transmembrane transport →	+2.191	+4.947	<.001	<.001	3	17
URINARY_TRACT	Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.146	+3.552	<.001	<.001	3	11
PANCREAS	Polyol transmembrane transport →	+0.841	+3.170	<.001	<.001	3	10
STOMACH	Bundle of His cell to Purkinje myocyte communication →	+0.250	+2.126	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,248 associations by consensus.

Urea transmembrane transport by AQP3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →