AQP2

Across TCGA patient cohorts, AQP2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible AQP2-associated genes across cancer lineages are Preadipocytes and GMP. Each is linked with AQP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AQP2-to-partner and partner-to-AQP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Preadipocytes grouped by AQP2-low versus AQP2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP2→partner) and Y-score (partner→AQP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	Preadipocytes →	+0.041	+3.527	<.001	.033	3	2
COAD	GMP →	+0.077	+3.562	.006	.015	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Preadipocytes by AQP2 expression — BLCA

Explore this box plot interactively →