AQP12B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AQP12B RNA expression is significantly associated with the protein abundance of many other proteins, with 7,405 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AQP12B-associated proteins across cancer lineages are ADAM17_S791, HEATR3, and APC_S1774. Each is linked with AQP12B in more than 1 cancer types. Because this analysis shows association rather than direction, both AQP12B-to-partner and partner-to-AQP12B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP12B→partner) and Y-score (partner→AQP12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACADAM17_S791 →-0.727-0.786<.001<.00132
OVHEATR3 →-0.267-0.129.007.00832
PDACAPC_S1774 →-0.892-1.015<.001<.00132
COADCREBBP →+0.325+0.244.001<.00132
PDACAHCTF1_S1232 →+0.333+0.769<.001<.00132
PDACDIDO1 →+0.158+0.738<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,405 associations by consensus.

Exploration