Across TCGA patient cohorts, AQP12B mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AQP12B-associated genes across cancer lineages are Neurons, DC, and Megakaryocytes. Each is linked with AQP12B in more than 1 cancer types. Because this analysis shows association rather than direction, both AQP12B-to-partner and partner-to-AQP12B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP12B→partner) and Y-score (partner→AQP12B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Neurons →	+0.023	+3.058	.021	.018	3	1
UCEC	DC →	+0.023	+3.234	.039	.009	3	1
UCEC	Megakaryocytes →	-0.027	-3.127	.047	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

AQP12B survival (RNA) · tumor vs normal (RNA) · all AQP12B data types