AQP1

Across TCGA patient cohorts, AQP1 mutation is significantly associated with the RNA expression of many other genes, with 738 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AQP1-associated genes across cancer lineages are RN7SKP188, RNU6-419P, and LINC00293. Each is linked with AQP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AQP1-to-partner and partner-to-AQP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP188 grouped by AQP1-low versus AQP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP1→partner) and Y-score (partner→AQP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP188 →	+0.135	+3.027	<.001	.007	3	2
LUAD	RNU6-419P →	+0.587	+4.628	.002	.004	3	2
LUAD	LINC00293 →	+0.022	+4.481	<.001	.009	3	2
CESC	NF1P10 →	+0.101	+5.569	.005	.002	3	2
SKCM	MIR3667 →	+0.353	+2.340	<.001	.009	3	2
COAD	RNU6-1050P →	+0.792	+4.951	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 738 associations by consensus.

RN7SKP188 by AQP1 expression — UCEC

Explore this box plot interactively →