Across TCGA cell cohorts, APRT RNA expression is significantly associated with the go_rna of many other GO terms, with 2,668 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible APRT-associated GO terms across cancer lineages are tRNA thio-modification, tRNA wobble position uridine thiolation, and Vesicle uncoating. Each is linked with APRT in more than 13 cancer types. Because this analysis shows association rather than direction, both APRT-to-partner and partner-to-APRT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APRT→partner) and Y-score (partner→APRT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	tRNA thio-modification →	+0.104	+0.696	<.001	<.001	3	14
BLOOD_Lymphoma	tRNA wobble position uridine thiolation →	+0.102	+0.581	<.001	.003	3	11
LUNG_NSCLC_LUSC	Vesicle uncoating →	+0.146	+0.596	<.001	.003	3	10
BREAST	Peptidyl-methionine modification →	+0.219	+0.943	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Iron-sulfur cluster assembly →	+0.085	+0.858	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Metallo-sulfur cluster assembly →	+0.085	+0.858	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,668 associations by consensus.

Exploration

APRT survival (RNA) · tumor vs normal (RNA) · all APRT data types