APPBP2

Across TCGA patient cohorts, APPBP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,093 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APPBP2-associated proteins across cancer lineages are VEZF1, DYNLL2, and BCAS3. Each is linked with APPBP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both APPBP2-to-partner and partner-to-APPBP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APPBP2 versus VEZF1 in BRCA, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APPBP2→partner) and Y-score (partner→APPBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VEZF1 →	+0.601	+0.682	<.001	<.001	3	5
BRCA	DYNLL2 →	+0.423	+0.592	<.001	<.001	3	5
BRCA	BCAS3 →	+0.204	+0.462	<.001	<.001	3	5
GBM	VSIR →	-0.650	-0.528	<.001	<.001	3	5
GBM	HSP90B1_S447 →	-0.595	-0.476	<.001	<.001	3	5
HNSC	MSI2 →	+0.442	+0.432	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,093 associations by consensus.

APPBP2 vs VEZF1 — BRCA

Explore this scatter interactively →