APOOL

Across TCGA patient cohorts, APOOL RNA expression is significantly associated with the protein abundance of many other proteins, with 10,772 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible APOOL-associated proteins across cancer lineages are HTATSF1, EVI2B, and RNF5. Each is linked with APOOL in more than 4 cancer types. Because this analysis shows association rather than direction, both APOOL-to-partner and partner-to-APOOL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APOOL versus HTATSF1 in COAD, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APOOL→partner) and Y-score (partner→APOOL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HTATSF1 →	+0.358	+0.493	<.001	<.001	3	5
BRCA	EVI2B →	-0.512	-0.619	.004	.001	3	5
LSCC	RNF5 →	+0.489	+0.378	<.001	.002	3	4
HNSC	CUL4B →	+0.287	+0.795	<.001	<.001	3	4
GBM	ALYREF →	+0.403	+0.505	<.001	.003	3	4
BRCA	TCEAL1 →	+0.521	+0.396	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,772 associations by consensus.

APOOL vs HTATSF1 — COAD

Explore this scatter interactively →