APOOL

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, APOOL protein abundance is significantly associated with the protein abundance of many other proteins, with 16,287 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible APOOL-associated proteins across cancer lineages are MECR, OGDH, and AIFM1. Each is linked with APOOL in more than 9 cancer types. Because this analysis shows association rather than direction, both APOOL-to-partner and partner-to-APOOL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APOOL versus MECR in OV, with a Pearson correlation of 0.54.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APOOL→partner) and Y-score (partner→APOOL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMECR →+0.406+0.262<.001<.001310
COADOGDH →+0.317+0.406<.001<.001310
OVAIFM1 →+0.497+0.332.002<.00139
OVACAD8 →+0.597+0.390<.001<.00139
PDACSLC30A9 →+0.509+0.394<.001<.00139
OVCPT2 →+0.439+0.418<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,287 associations by consensus.

APOOL vs MECR — OV

Per-sample scatter of APOOL vs MECR in OV (Pearson r = 0.54).

Explore this scatter interactively →

Exploration