Across TCGA cell cohorts, APOO RNA expression is significantly associated with the go_rna of many other GO terms, with 4,447 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible APOO-associated GO terms across cancer lineages are Cristae formation, Cell-matrix adhesion, and Regulation of Rho protein signal transduction. Each is linked with APOO in more than 12 cancer types. Because this analysis shows association rather than direction, both APOO-to-partner and partner-to-APOO results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APOO→partner) and Y-score (partner→APOO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Cristae formation →	+0.130	+1.151	<.001	.002	3	13
PANCREAS	Cell-matrix adhesion →	-0.096	-0.719	.002	.004	3	13
LARGE_INTESTINE	Regulation of Rho protein signal transduction →	-0.083	-0.789	.001	<.001	3	13
OESOPHAGUS	Cell junction assembly →	-0.094	-0.995	<.001	.004	3	12
PANCREAS	Regulation of angiogenesis →	-0.080	-0.993	<.001	<.001	3	11
BLOOD_Myeloma	DNA replication initiation →	+0.133	+0.742	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,447 associations by consensus.

Exploration

APOO survival (RNA) · tumor vs normal (RNA) · all APOO data types