APONP

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, APONP RNA expression is significantly associated with the go_rna of many other GO terms, with 6,320 significant associations in total. STAD shows the largest number of these associations.

The most reproducible APONP-associated GO terms across cancer lineages are Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, Regulation of DNA repair, and Positive regulation of chromosome organization. Each is linked with APONP in more than 9 cancer types. Because this analysis shows association rather than direction, both APONP-to-partner and partner-to-APONP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APONP→partner) and Y-score (partner→APONP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADObsolete nuclear-transcribed mRNA catabolic process, exonucleolytic →+0.095+0.173<.001<.001310
STADRegulation of DNA repair →+0.096+0.203<.001<.001310
STADPositive regulation of chromosome organization →+0.106+0.195<.001<.00139
STADMicrotubule polymerization or depolymerization →+0.087+0.195<.001<.00139
STADRegulation of microtubule polymerization →+0.083+0.194<.001<.00139
STADMethylation →+0.088+0.219<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,320 associations by consensus.

Exploration