Across TCGA patient cohorts, APOM protein abundance is significantly associated with the RNA expression of many other genes, with 11,482 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible APOM-associated genes across cancer lineages are IL6, CD93, and LYVE1. Each is linked with APOM in more than 8 cancer types. Because this analysis shows association rather than direction, both APOM-to-partner and partner-to-APOM results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOM→partner) and Y-score (partner→APOM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	IL6 →	+1.350	+0.393	<.001	<.001	3	9
BRCA	CD93 →	+0.825	+0.693	<.001	<.001	3	7
GBM	LYVE1 →	+1.794	+0.583	<.001	<.001	3	7
OV	THBS1 →	+1.448	+0.606	<.001	<.001	3	7
CCRCC	AVPR1A →	+0.912	+0.444	.004	.004	3	7
OV	FLT1 →	+0.835	+0.586	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,482 associations by consensus.

Exploration

APOM survival (RNA) · tumor vs normal (RNA) · all APOM data types