APOH

Across TCGA patient cohorts, APOH mutation is significantly associated with the RNA expression of many other genes, with 3,380 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible APOH-associated genes across cancer lineages are ARF1P1, CHCHD4, and SYNJ2BP-COX16. Each is linked with APOH in more than 2 cancer types. Because this analysis shows association rather than direction, both APOH-to-partner and partner-to-APOH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARF1P1 grouped by APOH-low versus APOH-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOH→partner) and Y-score (partner→APOH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ARF1P1 →	+0.499	+4.324	<.001	.007	3	3
UCEC	CHCHD4 →	+0.338	+1.869	.006	.005	3	3
SKCM	SYNJ2BP-COX16 →	+0.295	+1.938	.003	.009	3	3
UCEC	TMEM203 →	+0.362	+2.290	.004	.001	3	3
UCEC	PCGF7P →	+0.195	+2.431	<.001	.001	3	2
SKCM	ESS2 →	+0.311	+3.347	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,380 associations by consensus.

ARF1P1 by APOH expression — COAD

Explore this box plot interactively →