APOH

Across TCGA cell cohorts, APOH RNA expression is significantly associated with the go_rna of many other GO terms, with 2,269 significant associations in total. BONE shows the largest number of these associations.

The most reproducible APOH-associated GO terms across cancer lineages are Negative regulation of cholesterol import, Chylomicron remodeling, and Trans-synaptic signaling by BDNF, modulating synaptic transmission. Each is linked with APOH in more than 4 cancer types. Because this analysis shows association rather than direction, both APOH-to-partner and partner-to-APOH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cholesterol import grouped by APOH-low versus APOH-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APOH→partner) and Y-score (partner→APOH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of cholesterol import →	+2.101	+5.442	<.001	<.001	3	5
LIVER	Chylomicron remodeling →	+2.261	+5.849	<.001	<.001	3	5
LIVER	Trans-synaptic signaling by BDNF, modulating synaptic transmission →	-1.402	-5.068	.001	<.001	3	4
LIVER	Trans-synaptic signaling by BDNF →	-1.402	-5.068	.001	<.001	3	4
BONE	Myotube differentiation →	-0.184	-0.809	<.001	<.001	3	4
BONE	Equilibrioception →	+1.649	+0.673	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,269 associations by consensus.

Negative regulation of cholesterol import by APOH expression — LIVER

Explore this box plot interactively →