APOH

Across TCGA cell cohorts, APOH mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible APOH-associated genes across cancer lineages are UGT2B10, ARGFX, and PFN3. Each is linked with APOH in more than 1 cancer types. Because this analysis shows association rather than direction, both APOH-to-partner and partner-to-APOH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT2B10 grouped by APOH-low versus APOH-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOH→partner) and Y-score (partner→APOH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	UGT2B10 →	+0.006	+4.977	<.001	.007	3	1
LARGE_INTESTINE	ARGFX →	+0.015	+5.022	<.001	.002	3	1
LARGE_INTESTINE	PFN3 →	+0.166	+4.467	<.001	.004	3	1
LARGE_INTESTINE	CENPVL1 →	+0.182	+4.095	<.001	.009	3	1
STOMACH	IL10 →	+0.891	+3.632	.006	.009	3	1
STOMACH	BPIFA1 →	+0.096	+3.830	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

UGT2B10 by APOH expression — SKIN

Explore this box plot interactively →