Across TCGA patient cohorts, APOD protein abundance is significantly associated with the RNA expression of many other genes, with 7,668 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible APOD-associated genes across cancer lineages are LRRC32, EBF2, and PHYHIP. Each is linked with APOD in more than 5 cancer types. Because this analysis shows association rather than direction, both APOD-to-partner and partner-to-APOD results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOD→partner) and Y-score (partner→APOD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LRRC32 →	+1.057	+1.219	<.001	<.001	3	6
PDAC	EBF2 →	+0.663	+0.558	<.001	<.001	3	6
COAD	PHYHIP →	+0.497	+0.602	.001	<.001	3	6
BRCA	ISM1 →	+1.340	+1.593	<.001	<.001	3	5
HNSC	THBS4 →	+2.048	+0.464	<.001	<.001	3	5
OV	PTGIS →	+1.508	+0.609	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,668 associations by consensus.

Exploration

APOD survival (RNA) · tumor vs normal (RNA) · all APOD data types