APOD

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, APOD mutation is significantly associated with the RNA expression of many other genes, with 343 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible APOD-associated genes across cancer lineages are MIR921, SNORA1B, and MIR138-1. Each is linked with APOD in more than 1 cancer types. Because this analysis shows association rather than direction, both APOD-to-partner and partner-to-APOD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOD→partner) and Y-score (partner→APOD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMIR921 →+0.574+5.137<.001.00732
CESCSNORA1B →+0.303+4.320.005.00731
CESCMIR138-1 →+0.513+4.760<.001.00331
CESCRNU6ATAC26P →+0.320+4.234.001.00831
CESCPPIHP2 →+0.093+4.503<.001.00531
CESCSNORD111B →+0.457+4.409.002.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 343 associations by consensus.

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