Across TCGA patient cohorts, APOD mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible APOD-associated genes across cancer lineages are p62 Lck ligand, IGFBP2, and MSH6. Each is linked with APOD in more than 1 cancer types. Because this analysis shows association rather than direction, both APOD-to-partner and partner-to-APOD results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOD→partner) and Y-score (partner→APOD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.366	+2.459	.019	.020	3	2
UCEC	IGFBP2 →	-0.932	-2.459	.002	.020	3	1
UCEC	MSH6 →	-0.371	-2.999	.020	.035	3	1
UCEC	PDK1_pS241 →	+0.163	+3.000	.049	.036	3	1
UCEC	PKC-a_pS657 →	+0.396	+3.009	.031	.019	3	1
UCEC	PKC-a →	+0.467	+2.459	.016	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

APOD survival (RNA) · tumor vs normal (RNA) · all APOD data types