APOC2

Across TCGA patient cohorts, APOC2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible APOC2-associated genes across cancer lineages are FAM197Y1, TAF9P1, and RNU6-1236P. Each is linked with APOC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both APOC2-to-partner and partner-to-APOC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM197Y1 grouped by APOC2-low versus APOC2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOC2→partner) and Y-score (partner→APOC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM197Y1 →	+0.049	+8.066	<.001	.007	3	1
UCEC	TAF9P1 →	+0.069	+8.066	<.001	.007	3	1
LUSC	RNU6-1236P →	+0.312	+7.924	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

FAM197Y1 by APOC2 expression — UCEC

Explore this box plot interactively →