APOC2

Across TCGA cell cohorts, APOC2 protein abundance is significantly associated with the RNA expression of many other genes, with 140 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible APOC2-associated genes across cancer lineages are SLC15A3, C1orf127, and MIGA2. Each is linked with APOC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both APOC2-to-partner and partner-to-APOC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APOC2 versus SLC15A3 in BLOOD_Leukemia, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOC2→partner) and Y-score (partner→APOC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC15A3 →	+2.459	+2.740	.003	<.001	3	2
BLOOD_Leukemia	C1orf127 →	+0.639	+3.139	.007	.003	3	2
LUNG_SCLC	MIGA2 →	+0.404	+3.261	.009	.008	3	1
LUNG_SCLC	TEX55 →	+1.500	+3.261	.002	.008	3	1
SKIN	SLC9B1 →	+0.269	+1.447	<.001	.005	3	1
BLOOD_Leukemia	MGRN1 →	+0.745	+2.793	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 140 associations by consensus.

APOC2 vs SLC15A3 — BLOOD_Leukemia

Explore this scatter interactively →