APOBEC3H

Across TCGA cell cohorts, APOBEC3H RNA expression is significantly associated with the go_rna of many other GO terms, with 3,317 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible APOBEC3H-associated GO terms across cancer lineages are Cellular response to cell-matrix adhesion, Response to vitamin B1, and GDF15-GFRAL signaling pathway. Each is linked with APOBEC3H in more than 11 cancer types. Because this analysis shows association rather than direction, both APOBEC3H-to-partner and partner-to-APOBEC3H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to cell-matrix adhesion grouped by APOBEC3H-low versus APOBEC3H-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APOBEC3H→partner) and Y-score (partner→APOBEC3H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Cellular response to cell-matrix adhesion →	+0.348	+0.661	<.001	.003	2	12
KIDNEY	Response to vitamin B1 →	+0.161	+0.549	<.001	.009	3	8
SOFT_TISSUE	GDF15-GFRAL signaling pathway →	+1.158	+0.381	<.001	<.001	3	8
BREAST	Reduction of food intake in response to dietary excess →	+1.402	+0.376	<.001	.006	2	9
KIDNEY	Positive regulation of defense response to virus by host →	+0.149	+0.843	<.001	.001	3	7
PANCREAS	Regulation of defense response to virus by host →	+0.124	+0.535	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,317 associations by consensus.

Cellular response to cell-matrix adhesion by APOBEC3H expression — KIDNEY

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