APOA4

Across TCGA patient cohorts, APOA4 protein abundance is significantly associated with the protein abundance of many other proteins, with 29,711 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APOA4-associated proteins across cancer lineages are AGT, AHSG_S138, and A2M. Each is linked with APOA4 in more than 9 cancer types. Because this analysis shows association rather than direction, both APOA4-to-partner and partner-to-APOA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APOA4 versus AGT in CCRCC, with a Pearson correlation of 0.75.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APOA4→partner) and Y-score (partner→APOA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	AGT →	+0.763	+0.907	<.001	<.001	3	10
BRCA	AHSG_S138 →	+0.884	+0.756	<.001	<.001	3	10
OV	A2M →	+0.764	+0.881	<.001	<.001	3	10
BRCA	AMBP →	+0.694	+0.847	<.001	<.001	3	10
BRCA	APCS →	+1.224	+0.715	<.001	<.001	3	10
CCRCC	APOA1 →	+1.079	+0.981	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 29,711 associations by consensus.

APOA4 vs AGT — CCRCC

Explore this scatter interactively →