APOA4

Across TCGA cell cohorts, APOA4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,780 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible APOA4-associated genes across cancer lineages are OVCA2, PAFAH1B1, and RPA1. Each is linked with APOA4 in more than 5 cancer types. Because this analysis shows association rather than direction, both APOA4-to-partner and partner-to-APOA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APOA4 versus OVCA2 in BLOOD_Lymphoma, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOA4→partner) and Y-score (partner→APOA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OVCA2 →	+0.635	+0.673	<.001	.001	3	6
BLOOD_Lymphoma	PAFAH1B1 →	+0.965	+0.807	<.001	<.001	3	6
BREAST	RPA1 →	+0.973	+1.207	.003	.001	3	5
BLOOD_Leukemia	CYB5D2 →	+0.607	+0.522	<.001	<.001	3	5
STOMACH	VPS53 →	+0.992	+0.743	.003	.001	3	5
BLOOD_Lymphoma	ANKFY1 →	+1.159	+0.867	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,780 associations by consensus.

APOA4 vs OVCA2 — BLOOD_Lymphoma

Explore this scatter interactively →