APOA1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, APOA1 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible APOA1-associated genes across cancer lineages are MPP. Each is linked with APOA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both APOA1-to-partner and partner-to-APOA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by APOA1-low versus APOA1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOA1→partner) and Y-score (partner→APOA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCMPP →+0.034+4.694<.001.01432
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MPP by APOA1 expression — LUSC

Box plot of MPP in APOA1-low vs APOA1-high samples in LUSC.

Explore this box plot interactively →

Exploration