APLP1

Across TCGA patient cohorts, APLP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,399 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APLP1-associated proteins across cancer lineages are MAP1B, MAP1B_S995, and KIF1A_S1370. Each is linked with APLP1 in more than 4 cancer types. Because this analysis shows association rather than direction, both APLP1-to-partner and partner-to-APLP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APLP1 versus MAP1B in HNSC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APLP1→partner) and Y-score (partner→APLP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MAP1B →	+0.735	+0.762	<.001	<.001	3	5
GBM	MAP1B_S995 →	+0.743	+1.003	<.001	<.001	3	5
LSCC	KIF1A_S1370 →	+1.436	+0.568	.006	.006	3	4
HNSC	MAP1A →	+0.477	+0.683	.001	.002	3	4
CCRCC	MAP1B_S1016 →	+0.804	+0.909	<.001	<.001	3	4
CCRCC	MAP1B_S1208 →	+0.429	+0.731	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,399 associations by consensus.

APLP1 vs MAP1B — HNSC

Explore this scatter interactively →