APLNR

Across TCGA patient cohorts, APLNR RNA expression is significantly associated with the protein abundance of many other proteins, with 18,152 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APLNR-associated proteins across cancer lineages are PPM1F, ITIH1, and LAMA4. Each is linked with APLNR in more than 8 cancer types. Because this analysis shows association rather than direction, both APLNR-to-partner and partner-to-APLNR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APLNR versus PPM1F in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APLNR→partner) and Y-score (partner→APLNR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PPM1F →	+0.294	+0.873	<.001	<.001	3	9
OV	ITIH1 →	+0.625	+1.127	<.001	<.001	3	8
OV	LAMA4 →	+0.644	+1.281	<.001	<.001	3	8
CCRCC	CLEC3B →	+0.679	+0.713	<.001	<.001	3	8
OV	COPZ2 →	+1.055	+1.301	<.001	<.001	3	8
UCEC	DPYSL3 →	+0.838	+0.952	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,152 associations by consensus.

APLNR vs PPM1F — BRCA

Explore this scatter interactively →