APLN

Across TCGA patient cohorts, APLN RNA expression is significantly associated with the protein abundance of many other proteins, with 12,098 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible APLN-associated proteins across cancer lineages are PLOD2, BMP1, and FLT1. Each is linked with APLN in more than 7 cancer types. Because this analysis shows association rather than direction, both APLN-to-partner and partner-to-APLN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APLN versus PLOD2 in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APLN→partner) and Y-score (partner→APLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PLOD2 →	+1.060	+1.206	<.001	<.001	3	8
OV	BMP1 →	+0.766	+0.870	.003	.008	3	7
GBM	FLT1 →	+0.652	+1.286	<.001	<.001	3	7
PDAC	ANGPT2 →	+0.674	+1.310	<.001	<.001	3	7
PDAC	LOXL2 →	+1.001	+1.265	<.001	<.001	3	7
PDAC	P4HA2 →	+0.847	+1.175	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,098 associations by consensus.

APLN vs PLOD2 — OV

Explore this scatter interactively →