API5

Across TCGA cell cohorts, API5 RNA expression is significantly associated with the RNA expression of many other genes, with 10,325 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible API5-associated genes across cancer lineages are CKAP5, HNRNPK, and QSER1. Each is linked with API5 in more than 18 cancer types. Because this analysis shows association rather than direction, both API5-to-partner and partner-to-API5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, API5 versus CKAP5 in LUNG_NSCLC_LUSC, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (API5→partner) and Y-score (partner→API5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	CKAP5 →	+1.005	+1.000	.001	.001	2	19
BREAST	HNRNPK →	+0.674	+0.907	<.001	<.001	2	19
LUNG_NSCLC_LUSC	QSER1 →	+1.228	+1.091	<.001	<.001	2	19
OESOPHAGUS	GTF2H1 →	+1.167	+1.131	<.001	<.001	3	18
BLOOD_Lymphoma	BCLAF1 →	+1.019	+0.740	<.001	<.001	3	17
BLOOD_Lymphoma	SYNCRIP →	+1.216	+0.898	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,325 associations by consensus.

API5 vs CKAP5 — LUNG_NSCLC_LUSC

Explore this scatter interactively →