APH1A

Across TCGA patient cohorts, APH1A RNA expression is significantly associated with the protein abundance of many other proteins, with 12,655 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible APH1A-associated proteins across cancer lineages are RPRD2, PRCC, and HDGF. Each is linked with APH1A in more than 7 cancer types. Because this analysis shows association rather than direction, both APH1A-to-partner and partner-to-APH1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APH1A versus RPRD2 in BRCA, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APH1A→partner) and Y-score (partner→APH1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RPRD2 →	+0.302	+0.490	<.001	<.001	3	8
UCEC	PRCC →	+0.341	+0.982	<.001	<.001	3	6
OV	HDGF →	+0.341	+0.386	.006	.001	3	6
BRCA	GATAD2B →	+0.312	+0.376	<.001	<.001	3	6
LSCC	ZNF687 →	+0.374	+0.518	<.001	<.001	3	5
LSCC	TRRAP →	+0.183	+0.313	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,655 associations by consensus.

APH1A vs RPRD2 — BRCA

Explore this scatter interactively →