APH1A

Across TCGA cell cohorts, APH1A mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. CNS shows the largest number of these associations.

The most reproducible APH1A-associated genes across cancer lineages are ACSM2B. Each is linked with APH1A in more than 1 cancer types. Because this analysis shows association rather than direction, both APH1A-to-partner and partner-to-APH1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACSM2B grouped by APH1A-low versus APH1A-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APH1A→partner) and Y-score (partner→APH1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ACSM2B →	+0.013	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

ACSM2B by APH1A expression — CNS

Explore this box plot interactively →