APEH

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, APEH protein abundance is significantly associated with the RNA expression of many other genes, with 15,346 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible APEH-associated genes across cancer lineages are VIRMA, SNRPE, and FBXO5. Each is linked with APEH in more than 4 cancer types. Because this analysis shows association rather than direction, both APEH-to-partner and partner-to-APEH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APEH versus VIRMA in COAD, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APEH→partner) and Y-score (partner→APEH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADVIRMA →-0.348-0.275.003<.00135
HNSCSNRPE →-1.028-0.203<.001<.00135
GBMFBXO5 →-1.040-0.469<.001<.00135
GBMTTK →-1.207-0.398<.001<.00135
GBMSTMN1 →-1.021-0.385<.001.00235
GBMCENPF →-1.418-0.399<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,346 associations by consensus.

APEH vs VIRMA — COAD

Per-sample scatter of APEH vs VIRMA in COAD (Pearson r = -0.28).

Explore this scatter interactively →

Exploration