APCDD1

Across TCGA cell cohorts, APCDD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,403 significant associations in total. BONE shows the largest number of these associations.

The most reproducible APCDD1-associated GO terms across cancer lineages are Regulation of G0 to G1 transition, Cellular respiration, and Energy derivation by oxidation of organic compounds. Each is linked with APCDD1 in more than 7 cancer types. Because this analysis shows association rather than direction, both APCDD1-to-partner and partner-to-APCDD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G0 to G1 transition grouped by APCDD1-low versus APCDD1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APCDD1→partner) and Y-score (partner→APCDD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of G0 to G1 transition →	+0.097	+1.402	<.001	<.001	3	8
OESOPHAGUS	Cellular respiration →	+0.083	+1.557	.005	.004	3	8
LUNG_SCLC	Energy derivation by oxidation of organic compounds →	+0.054	+1.466	<.001	.003	3	8
OVARY	ATP synthesis coupled electron transport →	+0.069	+1.029	.001	.003	3	8
OVARY	Mitochondrial ATP synthesis coupled electron transport →	+0.069	+1.029	.001	.003	3	8
LUNG_SCLC	Aerobic respiration →	+0.101	+2.024	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,403 associations by consensus.

Regulation of G0 to G1 transition by APCDD1 expression — BLOOD_Leukemia

Explore this box plot interactively →