APC2

Across TCGA cell cohorts, APC2 RNA expression is significantly associated with the RNA expression of many other genes, with 10,643 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible APC2-associated genes across cancer lineages are MEIS3, MCM3AP, and PKD1. Each is linked with APC2 in more than 11 cancer types. Because this analysis shows association rather than direction, both APC2-to-partner and partner-to-APC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APC2 versus MEIS3 in OVARY, with a Pearson correlation of 0.65.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APC2→partner) and Y-score (partner→APC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MEIS3 →	+2.791	+1.162	<.001	.002	3	12
SOFT_TISSUE	MCM3AP →	+1.368	+1.618	<.001	<.001	3	11
SOFT_TISSUE	PKD1 →	+1.697	+1.349	<.001	<.001	2	12
SOFT_TISSUE	DACT3 →	+1.367	+1.118	<.001	<.001	3	11
SOFT_TISSUE	ADGRL1 →	+2.542	+1.689	<.001	<.001	3	11
LUNG_NSCLC_LUSC	NLGN2 →	+2.253	+1.128	<.001	.004	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,643 associations by consensus.

APC2 vs MEIS3 — OVARY

Explore this scatter interactively →