APBB3

Across TCGA patient cohorts, APBB3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,408 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible APBB3-associated proteins across cancer lineages are FAM172A, SCYL2, and TBC1D9B. Each is linked with APBB3 in more than 4 cancer types. Because this analysis shows association rather than direction, both APBB3-to-partner and partner-to-APBB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APBB3 versus FAM172A in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APBB3→partner) and Y-score (partner→APBB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM172A →	+0.376	+0.771	<.001	<.001	3	5
OV	SCYL2 →	-0.186	-0.511	.004	.009	3	4
PDAC	TBC1D9B →	+0.155	+0.277	<.001	<.001	3	4
CCRCC	EMC8 →	-0.164	-0.339	<.001	<.001	3	4
LUAD	NOP2 →	-0.466	-0.404	<.001	<.001	3	4
GBM	AGO1 →	+0.233	+0.301	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,408 associations by consensus.

APBB3 vs FAM172A — BRCA

Explore this scatter interactively →