APBB3

Across TCGA patient cohorts, APBB3 protein abundance is significantly associated with the RNA expression of many other genes, with 171 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APBB3-associated genes across cancer lineages are TIMM9, MLYCD, and GSK3A. Each is linked with APBB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both APBB3-to-partner and partner-to-APBB3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APBB3 versus TIMM9 in GBM, with a Pearson correlation of -0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APBB3→partner) and Y-score (partner→APBB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TIMM9 →	-1.216	-0.246	.003	.001	3	1
GBM	MLYCD →	-0.583	-0.299	.004	.007	3	1
GBM	GSK3A →	-0.913	-0.303	.002	.007	3	1
GBM	SMG9 →	-0.718	-0.250	.009	.001	3	1
GBM	ACTR3C →	+1.276	+0.279	.005	.004	3	1
GBM	SUSD1 →	-1.723	-0.243	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 171 associations by consensus.

APBB3 vs TIMM9 — GBM

Explore this scatter interactively →