APBB3

Across TCGA cell cohorts, APBB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,906 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible APBB3-associated GO terms across cancer lineages are Protein polyglycylation, Calcium-independent cell-matrix adhesion, and Target-directed miRNA degradation. Each is linked with APBB3 in more than 17 cancer types. Because this analysis shows association rather than direction, both APBB3-to-partner and partner-to-APBB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyglycylation grouped by APBB3-low versus APBB3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APBB3→partner) and Y-score (partner→APBB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Protein polyglycylation →	+1.254	+0.982	.001	.003	3	18
URINARY_TRACT	Calcium-independent cell-matrix adhesion →	+0.236	+1.429	<.001	.002	3	16
OVARY	Target-directed miRNA degradation →	+0.115	+0.941	<.001	.001	2	16
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.137	-1.690	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.128	+1.322	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.137	-1.690	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,906 associations by consensus.

Protein polyglycylation by APBB3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →