APBB2

Across TCGA cell cohorts, APBB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,464 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible APBB2-associated GO terms across cancer lineages are Retrograde transport, endosome to Golgi, Regulation of cell-matrix adhesion, and Regulation of hippo signaling. Each is linked with APBB2 in more than 12 cancer types. Because this analysis shows association rather than direction, both APBB2-to-partner and partner-to-APBB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde transport, endosome to Golgi grouped by APBB2-low versus APBB2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APBB2→partner) and Y-score (partner→APBB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Retrograde transport, endosome to Golgi →	+0.076	+1.215	.003	.004	3	13
SKIN	Regulation of cell-matrix adhesion →	+0.083	+1.029	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of hippo signaling →	+0.103	+1.537	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of pinocytosis →	+0.130	+1.601	<.001	.001	3	12
STOMACH	Vesicle-mediated transport to the plasma membrane →	+0.075	+1.545	.002	.005	3	12
BONE	Endocytic recycling →	+0.057	+1.306	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,464 associations by consensus.

Retrograde transport, endosome to Golgi by APBB2 expression — OESOPHAGUS

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